It's tough to trust any institution, these days. But if you're gonna gamble on one, Médecins Sans Frontières (MSF) seems a pretty safe bet.
If you can't get over the whole cheese-eating surrender monkey thing, it's o.k. if you call them Doctors Without Borders.
Anyway, here's their current page on the ongoing horror in the Sudan.
And here, goddammit, is one of the most recent chapters in that ongoing horror.
If the holiday seasons moves you to make monetary contributions to do-gooder-types, there are few who do gooder than these.